資訊中心 > 產品文獻集 > Microarray Technology (15)

  ✔本篇論文使用華聯產品:OEM Array  
 Applied Mechanics And Materials . 2013 Jan. doi: 10.4028/www.scientific.net/AMM.284-287.315.
 Investigation of Hybridization Efficiency of a Sequence-Orientated Coaxial DNA Probe Microarryed on Biochips Using Atomic Force Microscope 
 Dan-kai Yang, Yane-shu Lin, Jun-yi Chen, Jui-chuang Wu
  Abstract
Two sequence-inversed probes were microarrayed on glass slides to study the hybridization efficiency with their DNA targets. The sequences of two targets were designed to be fully complementary to their shared DNA probe in a coaxial stacking configuration. The enhancement of the hybridization efficiency was investigated through the comparison between the stacking and individual hybridization configurations. AFM was used to measure the depths of two probes at different steps of hybridization. The results indicated that the depths increased as the hybridization proceeded. Probe#1, pre-hybridizing close to the chip surface, obtained a thicker depth than the other probe pre-hybridizing away from the chip surface, Probe#2. A hypothesis was proposed to explain how the depth variation was associated with the observed hybridization efficiency.
   

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  ✔本篇論文使用華聯產品:Array technology and applications  
 Journal Of Laboratory Automation. 2012, 17(6):405-407. doi: 10.1177/2211068212463689.
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  ✔本篇論文使用華聯產品:Array technology and applications  
 Neurology Today. 2011, 11(19): 24-27. doi: 10.1097/01.NT.0000407216.70062.aa.
 Evidence Report: Genetic, Metabolic Screening Useful in children with Intellectual Development Deficits
 
 
 Kurt Samson
  Abstract
Although there are challenges yet to be overcome in the diagnostic evaluation of children with unexplained global developmental delay or intellectual disability (GDD/ID), genetic and metabolic screening tests are increasingly useful, according to a review by the AAN Quality Standards Subcommittee and the Practice Committee of the Child Neurology Society. The review was published in the Sept. 28 online edition of Neurology. In an interview with Neurology Today, AAN subcommittee panelist David J. Michelson, MD, assistant professor of neurology and pediatrics at the Loma Linda University School of Medicine in California, discussed the fi ndings and their implications for clinicians.